Download Flare 9.0

Download Flare 9.0

Cresset Flare

Flare for ligand and structure-based drug design

Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.

Flare customers, typically computational and medicinal chemists across pharmaceuticals, biotechnology, academia, and other industries, value the platform as their ‘computational toolbox’. The software enables them to closely inspect the detail of their ligand-protein complexes, using a variety of methods to gain useful insights into their protein targets and ligand series. As our most feature-packed software package, both ligand-based and structure-based drug designers are supported to progress their lead optimization, with confidence.

By closely examining a wide portfolio of ideas and applying a large variety of methods, a large number of molecules can be reduced to a small collection, allowing only the very best molecules to be handed over for lab experiments. The outcome is not only a great reduction in time, energy, and lab resources, but also the greatest chances of success in later-stage drug development.

  • Support medicinal chemists in reaching results more efficiently
  • Progress lead optimization with confidence
  • Prioritize the best molecules to make
  • Visualize target structures and potential ligands with high-resolution 3D graphics
  • Develop a comprehensive understanding of molecular interactions and binding
  • Accurately predict the activity of congeneric ligands using cutting-edge Free Energy Perturbation (FEP) calculations
  • Build predictive QSAR models for activity and ADME properties
  • Gain an in-depth understanding of the SAR for your ligands
  • Enable communication with colleagues across the DMTA cycle, thanks to Flare’s seamless integration with Torx®

Download Cresset Flare 9.0

Download Flare 9.0

How to install Flare 9.0

Download all parts (If the file is split into multiple parts), then extract the file

Installation guide: install according to the instructions in the Readme.txt file

  • Disable anti-virus software when unpack and install
  • After the installation is done, open anti-virus software, add installation directory OR Cracked file to exclusion (Set in antivirus app OR windows security)